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Uniform Sampling of Steady States in Metabolic Networks: Heterogeneous Scales and Rounding
The uniform sampling of convex polytopes is an interesting computational problem with many applications in inference from linear constraints, but the performances of sampling algorithms can be affected by ill-conditioning. This is the case of inferring the feasible steady states in models of metabol...
Autores principales: | De Martino, Daniele, Mori, Matteo, Parisi, Valerio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388631/ https://www.ncbi.nlm.nih.gov/pubmed/25849140 http://dx.doi.org/10.1371/journal.pone.0122670 |
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