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Decrease in Plasma Levels of α-Synuclein Is Evident in Patients with Parkinson’s Disease after Elimination of Heterophilic Antibody Interference

There is substantial biochemical, pathological, and genetic evidence that α-synuclein (A-syn) is a principal molecule in the pathogenesis of Parkinson disease (PD). We previously reported that total A-syn levels in cerebrospinal fluid (CSF), measured with the specific enzyme-linked immunosorbent ass...

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Detalles Bibliográficos
Autores principales: Ishii, Ryotaro, Tokuda, Takahiko, Tatebe, Harutsugu, Ohmichi, Takuma, Kasai, Takashi, Nakagawa, Masanori, Mizuno, Toshiki, El-Agnaf, Omar M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388641/
https://www.ncbi.nlm.nih.gov/pubmed/25849645
http://dx.doi.org/10.1371/journal.pone.0123162