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New Point Mutations in Surface and Core Genes of Hepatitis B Virus Associated with Acute on Chronic Liver Failure Identified by Complete Genomic Sequencing

The objective of this study was to identify new viral biomarkers associated with acute on chronic liver failure (ACLF) by complete genomic sequencing of HBV. Hepatitis B virus mutations associated with ACLF were screened by Illumina high-throughput sequencing in twelve ACLF cases and twelve age-matc...

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Detalles Bibliográficos
Autores principales: Xu, Hangdi, Zhao, Mingfei, Lou, Guohua, Zheng, Min, Cao, Qingyi, Chen, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388673/
https://www.ncbi.nlm.nih.gov/pubmed/25849554
http://dx.doi.org/10.1371/journal.pone.0123139