Cullin3 - BTB Interface: A Novel Target for Stapled Peptides

Cullin3 (Cul3), a key factor of protein ubiquitination, is able to interact with dozens of different proteins containing a BTB (Bric-a-brac, Tramtrack and Broad Complex) domain. We here targeted the Cul3–BTB interface by using the intriguing approach of stabilizing the α-helical conformation of Cul3...

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Detalles Bibliográficos
Autores principales: de Paola, Ivan, Pirone, Luciano, Palmieri, Maddalena, Balasco, Nicole, Esposito, Luciana, Russo, Luigi, Mazzà, Daniela, Di Marcotullio, Lucia, Di Gaetano, Sonia, Malgieri, Gaetano, Vitagliano, Luigi, Pedone, Emilia, Zaccaro, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388676/
https://www.ncbi.nlm.nih.gov/pubmed/25848797
http://dx.doi.org/10.1371/journal.pone.0121149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388676/
https://www.ncbi.nlm.nih.gov/pubmed/25848797
http://dx.doi.org/10.1371/journal.pone.0121149

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