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Paraptosis Cell Death Induction by the Thiamine Analog Benfotiamine in Leukemia Cells
Benfotiamine is a synthetic thiamine analogue that stimulates transketolase, a cellular enzyme essential for glucose metabolism. Currently, benfotiamine is used to treat diabetic neuropathy. We recently reported that oral benfotiamine induced a temporary but remarkable recovery from acute myeloid le...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388699/ https://www.ncbi.nlm.nih.gov/pubmed/25849583 http://dx.doi.org/10.1371/journal.pone.0120709 |