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G-CSF Protects Human Brain Vascular Endothelial Cells Injury Induced by High Glucose, Free Fatty Acids and Hypoxia through MAPK and Akt Signaling

Granulocyte-colony stimulating factor (G-CSF) has been shown to play a neuroprotective role in ischemic stroke by mobilizing bone marrow (BM)-derived endothelial progenitor cells (EPCs), promoting angiogenesis, and inhibiting apoptosis. Impairments in mobilization and function of the BM-derived EPCs...

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Detalles Bibliográficos
Autores principales: Su, Jingjing, Zhou, Houguang, Tao, Yinghong, Guo, Jingchun, Guo, Zhuangli, Zhang, Shuo, Zhang, Yu, Huang, Yanyan, Tang, Yuping, Dong, Qiang, Hu, Renming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388714/
https://www.ncbi.nlm.nih.gov/pubmed/25849550
http://dx.doi.org/10.1371/journal.pone.0120707