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Interplay between Constraints, Objectives, and Optimality for Genome-Scale Stoichiometric Models

High-throughput data generation and genome-scale stoichiometric models have greatly facilitated the comprehensive study of metabolic networks. The computation of all feasible metabolic routes with these models, given stoichiometric, thermodynamic, and steady-state constraints, provides important ins...

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Detalles Bibliográficos
Autores principales: Maarleveld, Timo R., Wortel, Meike T., Olivier, Brett G., Teusink, Bas, Bruggeman, Frank J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388735/
https://www.ncbi.nlm.nih.gov/pubmed/25849486
http://dx.doi.org/10.1371/journal.pcbi.1004166