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Interplay between Constraints, Objectives, and Optimality for Genome-Scale Stoichiometric Models
High-throughput data generation and genome-scale stoichiometric models have greatly facilitated the comprehensive study of metabolic networks. The computation of all feasible metabolic routes with these models, given stoichiometric, thermodynamic, and steady-state constraints, provides important ins...
Autores principales: | Maarleveld, Timo R., Wortel, Meike T., Olivier, Brett G., Teusink, Bas, Bruggeman, Frank J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388735/ https://www.ncbi.nlm.nih.gov/pubmed/25849486 http://dx.doi.org/10.1371/journal.pcbi.1004166 |
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