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TGF-β1 Induced Transdifferentiation of RPE Cells is Mediated by TAK1

BACKGROUND AND AIM: Proliferative vitreoretinopathy (PVR) is an active process that develops as a complication upon retinal detachment (RD), accompanied by formation of fibrotic tissue. The main cells involved in the development of fibrotic tissue during PVR are the retinal pigment epithelial (RPE)...

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Detalles Bibliográficos
Autores principales: Dvashi, Zeev, Goldberg, Mordechai, Adir, Orit, Shapira, Michal, Pollack, Ayala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388737/
https://www.ncbi.nlm.nih.gov/pubmed/25849436
http://dx.doi.org/10.1371/journal.pone.0122229