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Radiological and Pathological Features Associated with IDH1-R132H Mutation Status and Early Mortality in Newly Diagnosed Anaplastic Astrocytic Tumours

BACKGROUND: Glioblastoma can occur either de novo or by the transformation of a low grade tumour; the majority of which harbor a mutation in isocitrate dehydrogenase (IDH1). Anaplastic tumours are high-grade gliomas that may represent the final step in the evolution of a secondary glioblastoma or th...

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Detalles Bibliográficos
Autores principales: Wasserman, Jason K., Nicholas, Garth, Yaworski, Rebecca, Wasserman, Anne-Marie, Woulfe, John M., Jansen, Gerard H., Chakraborty, Santanu, Nguyen, Thanh B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388816/
https://www.ncbi.nlm.nih.gov/pubmed/25849605
http://dx.doi.org/10.1371/journal.pone.0123890