Oxidation by Neutrophils-Derived HOCl Increases Immunogenicity of Proteins by Converting Them into Ligands of Several Endocytic Receptors Involved in Antigen Uptake by Dendritic Cells and Macrophages

The initiation of adaptive immune responses to protein antigens has to be preceded by their uptake by antigen presenting cells and intracellular proteolytic processing. Paradoxically, endocytic receptors involved in antigen uptake do not bind the majority of proteins, which may be the main reason wh...

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Detalles Bibliográficos
Autores principales: Biedroń, Rafał, Konopiński, Maciej K., Marcinkiewicz, Janusz, Józefowski, Szczepan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388828/
https://www.ncbi.nlm.nih.gov/pubmed/25849867
http://dx.doi.org/10.1371/journal.pone.0123293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388828/
https://www.ncbi.nlm.nih.gov/pubmed/25849867
http://dx.doi.org/10.1371/journal.pone.0123293

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