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Proteolysis of Virulence Regulator ToxR Is Associated with Entry of Vibrio cholerae into a Dormant State

Vibrio cholerae O1 is a natural inhabitant of aquatic environments and causes the diarrheal disease, cholera. Two of its primary virulence regulators, TcpP and ToxR, are localized in the inner membrane. TcpP is encoded on the Vibrio Pathogenicity Island (VPI), a horizontally acquired mobile genetic...

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Detalles Bibliográficos
Autores principales: Almagro-Moreno, Salvador, Kim, Tae K., Skorupski, Karen, Taylor, Ronald K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388833/
https://www.ncbi.nlm.nih.gov/pubmed/25849031
http://dx.doi.org/10.1371/journal.pgen.1005145