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The Level of Residual Dispersion Variation and the Power of Differential Expression Tests for RNA-Seq Data

RNA-Sequencing (RNA-Seq) has been widely adopted for quantifying gene expression changes in comparative transcriptome analysis. For detecting differentially expressed genes, a variety of statistical methods based on the negative binomial (NB) distribution have been proposed. These methods differ in...

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Detalles Bibliográficos
Autores principales: Mi, Gu, Di, Yanming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388866/
https://www.ncbi.nlm.nih.gov/pubmed/25849826
http://dx.doi.org/10.1371/journal.pone.0120117