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The Level of Residual Dispersion Variation and the Power of Differential Expression Tests for RNA-Seq Data
RNA-Sequencing (RNA-Seq) has been widely adopted for quantifying gene expression changes in comparative transcriptome analysis. For detecting differentially expressed genes, a variety of statistical methods based on the negative binomial (NB) distribution have been proposed. These methods differ in...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388866/ https://www.ncbi.nlm.nih.gov/pubmed/25849826 http://dx.doi.org/10.1371/journal.pone.0120117 |