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The soluble CTLA-4 receptor and its role in autoimmune diseases: an update

CTLA-4, initially described as a membranebound molecule, is a costimulatory receptor transducing a potent inhibitory signal. Increasing evidence shows the CTLA-4 gene to be an important susceptibility locus for autoimmune endocrinopathies and other autoimmune disorders. A soluble form of cytotoxic T...

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Detalles Bibliográficos
Autores principales: Saverino, Daniele, Simone, Rita, Bagnasco, Marcello, Pesce, Giampaola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389044/
https://www.ncbi.nlm.nih.gov/pubmed/26000110
http://dx.doi.org/10.1007/s13317-010-0011-7