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Blocking type TSH receptor antibodies

TSH receptor (TSHR) autoantibodies (TRAbs) play a key role in the pathogenesis of Graves’ disease. In the majority of patients, TRAbs stimulate thyroid hormone synthesis via activation of the TSHR (stimulating TRAbs, TSHR agonists). In some patients, TRAbs bind to the receptor but do not cause activ...

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Detalles Bibliográficos
Autores principales: Furmaniak, Jadwiga, Sanders, Jane, Rees Smith, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389084/
https://www.ncbi.nlm.nih.gov/pubmed/26000138
http://dx.doi.org/10.1007/s13317-012-0028-1