Methotrexate toxicity treated with continuous venovenous hemofiltration, leucovorin and glucarpidase

High-dose methotrexate (MTX) can produce acute kidney injury, impairing MTX elimination. Continuous venovenous hemofiltration (CVVH) may enhance elimination in this setting, although its use is largely unstudied. A 79-year-old man received IV MTX for central nervous system lymphoma, and over a 34-h...

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Detalles Bibliográficos
Autores principales: Connors, Nicholas J., Sise, Meghan E., Nelson, Lewis S., Hoffman, Robert S., Smith, Silas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Original Contributions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389132/
https://www.ncbi.nlm.nih.gov/pubmed/25859377
http://dx.doi.org/10.1093/ckj/sfu093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389132/
https://www.ncbi.nlm.nih.gov/pubmed/25859377
http://dx.doi.org/10.1093/ckj/sfu093

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