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Methotrexate toxicity treated with continuous venovenous hemofiltration, leucovorin and glucarpidase
High-dose methotrexate (MTX) can produce acute kidney injury, impairing MTX elimination. Continuous venovenous hemofiltration (CVVH) may enhance elimination in this setting, although its use is largely unstudied. A 79-year-old man received IV MTX for central nervous system lymphoma, and over a 34-h...
Autores principales: | Connors, Nicholas J., Sise, Meghan E., Nelson, Lewis S., Hoffman, Robert S., Smith, Silas W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389132/ https://www.ncbi.nlm.nih.gov/pubmed/25859377 http://dx.doi.org/10.1093/ckj/sfu093 |
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