Small Molecule Ice Recrystallization Inhibitors Enable Freezing of Human Red Blood Cells with Reduced Glycerol Concentrations

In North America, red blood cells (RBCs) are cryopreserved in a clinical setting using high glycerol concentrations (40% w/v) with slow cooling rates (~1°C/min) prior to storage at −80°C, while European protocols use reduced glycerol concentrations with rapid freezing rates. After thawing and prior...

Descripción completa

Detalles Bibliográficos
Autores principales: Capicciotti, Chantelle J., Kurach, Jayme D. R., Turner, Tracey R., Mancini, Ross S., Acker, Jason P., Ben, Robert N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389209/
https://www.ncbi.nlm.nih.gov/pubmed/25851700
http://dx.doi.org/10.1038/srep09692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389209/
https://www.ncbi.nlm.nih.gov/pubmed/25851700
http://dx.doi.org/10.1038/srep09692

Ejemplares similares