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Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control

DNA replication stress is a source of genomic instability. Here we identify changed mutation rate 1 (Cmr1) as a factor involved in the response to DNA replication stress in Saccharomyces cerevisiae and show that Cmr1—together with Mrc1/Claspin, Pph3, the chaperonin containing TCP1 (CCT) and 25 other...

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Detalles Bibliográficos
Autores principales: Gallina, Irene, Colding, Camilla, Henriksen, Peter, Beli, Petra, Nakamura, Kyosuke, Offman, Judith, Mathiasen, David P., Silva, Sonia, Hoffmann, Eva, Groth, Anja, Choudhary, Chunaram, Lisby, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389229/
https://www.ncbi.nlm.nih.gov/pubmed/25817432
http://dx.doi.org/10.1038/ncomms7533