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Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control
DNA replication stress is a source of genomic instability. Here we identify changed mutation rate 1 (Cmr1) as a factor involved in the response to DNA replication stress in Saccharomyces cerevisiae and show that Cmr1—together with Mrc1/Claspin, Pph3, the chaperonin containing TCP1 (CCT) and 25 other...
Autores principales: | Gallina, Irene, Colding, Camilla, Henriksen, Peter, Beli, Petra, Nakamura, Kyosuke, Offman, Judith, Mathiasen, David P., Silva, Sonia, Hoffmann, Eva, Groth, Anja, Choudhary, Chunaram, Lisby, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389229/ https://www.ncbi.nlm.nih.gov/pubmed/25817432 http://dx.doi.org/10.1038/ncomms7533 |
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