A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy

Although recent methods for the engineering of antibody–drug conjugates (ADCs) have gone some way to addressing the challenging issues of ADC construction, significant hurdles still remain. There is clear demand for the construction of novel ADC platforms that offer greater stability, homogeneity an...

Descripción completa

Detalles Bibliográficos
Autores principales: Maruani, Antoine, Smith, Mark E.B., Miranda, Enrique, Chester, Kerry A., Chudasama, Vijay, Caddick, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389247/
https://www.ncbi.nlm.nih.gov/pubmed/25824906
http://dx.doi.org/10.1038/ncomms7645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389247/
https://www.ncbi.nlm.nih.gov/pubmed/25824906
http://dx.doi.org/10.1038/ncomms7645

Ejemplares similares