Cargando…
A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy
Although recent methods for the engineering of antibody–drug conjugates (ADCs) have gone some way to addressing the challenging issues of ADC construction, significant hurdles still remain. There is clear demand for the construction of novel ADC platforms that offer greater stability, homogeneity an...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Pub. Group
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389247/ https://www.ncbi.nlm.nih.gov/pubmed/25824906 http://dx.doi.org/10.1038/ncomms7645 |