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Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss
Immunglobulin G (IgG) sialylation represents a key checkpoint that determines the engagement of pro- or anti-inflammatory Fcγ receptors (FcγR) and the direction of the immune response. Whether IgG sialylation influences osteoclast differentiation and subsequently bone architecture has not been deter...
Autores principales: | Harre, Ulrike, Lang, Stefanie C., Pfeifle, René, Rombouts, Yoann, Frühbeißer, Sabine, Amara, Khaled, Bang, Holger, Lux, Anja, Koeleman, Carolien A., Baum, Wolfgang, Dietel, Katharina, Gröhn, Franziska, Malmström, Vivianne, Klareskog, Lars, Krönke, Gerhard, Kocijan, Roland, Nimmerjahn, Falk, Toes, René E. M., Herrmann, Martin, Scherer, Hans Ulrich, Schett, Georg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389255/ https://www.ncbi.nlm.nih.gov/pubmed/25825024 http://dx.doi.org/10.1038/ncomms7651 |
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