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Direct and rapid mass spectral fingerprinting of maternal urine for the detection of Down syndrome pregnancy

BACKGROUND: The established methods of antenatal screening for Down syndrome are based on immunoassay for a panel of maternal serum biomarkers together with ultrasound measures. Recently, genetic analysis of maternal plasma cell free (cf) DNA has begun to be used but has a number of limitations incl...

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Detalles Bibliográficos
Autores principales: Iles, Ray K, Shahpari, Maryam E, Cuckle, Howard, Butler, Stephen A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389308/
https://www.ncbi.nlm.nih.gov/pubmed/25878568
http://dx.doi.org/10.1186/s12014-015-9082-9