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Direct and rapid mass spectral fingerprinting of maternal urine for the detection of Down syndrome pregnancy
BACKGROUND: The established methods of antenatal screening for Down syndrome are based on immunoassay for a panel of maternal serum biomarkers together with ultrasound measures. Recently, genetic analysis of maternal plasma cell free (cf) DNA has begun to be used but has a number of limitations incl...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389308/ https://www.ncbi.nlm.nih.gov/pubmed/25878568 http://dx.doi.org/10.1186/s12014-015-9082-9 |