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The clinical and functional significance of c-Met in breast cancer: a review

c-Met is a receptor tyrosine kinase that upon binding of its ligand, hepatocyte growth factor (HGF), activates downstream pathways with diverse cellular functions that are important in organ development and cancer progression. Anomalous c-Met signalling has been described in a variety of cancer type...

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Detalles Bibliográficos
Autores principales: Ho-Yen, Colan M, Jones, J Louise, Kermorgant, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389345/
https://www.ncbi.nlm.nih.gov/pubmed/25887320
http://dx.doi.org/10.1186/s13058-015-0547-6