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Elementary properties of Ca(2+) channels and their influence on multivesicular release and phase-locking at auditory hair cell ribbon synapses

Voltage-gated calcium (Ca(v)1.3) channels in mammalian inner hair cells (IHCs) open in response to sound and the resulting Ca(2+) entry triggers the release of the neurotransmitter glutamate onto afferent terminals. At low to mid sound frequencies cell depolarization follows the sound sinusoid and p...

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Detalles Bibliográficos
Autores principales: Magistretti, Jacopo, Spaiardi, Paolo, Johnson, Stuart L., Masetto, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389406/
https://www.ncbi.nlm.nih.gov/pubmed/25904847
http://dx.doi.org/10.3389/fncel.2015.00123