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Antigiardial activity of novel triazolyl-quinolone-based chalcone derivatives: when oxygen makes the difference

Giardiasis is a common diarrheal disease worldwide caused by the protozoan parasite Giardia intestinalis. It is urgent to develop novel drugs to treat giardiasis, due to increasing clinical resistance to the gold standard drug metronidazole (MTZ). New potential antiparasitic compounds are usually te...

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Detalles Bibliográficos
Autores principales: Bahadur, Vijay, Mastronicola, Daniela, Singh, Amit K., Tiwari, Hemandra K., Pucillo, Leopoldo P., Sarti, Paolo, Singh, Brajendra K., Giuffrè, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389562/
https://www.ncbi.nlm.nih.gov/pubmed/25904901
http://dx.doi.org/10.3389/fmicb.2015.00256