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Strategies for B-Cell Receptor Repertoire Analysis in Primary Immunodeficiencies: From Severe Combined Immunodeficiency to Common Variable Immunodeficiency

The antigen receptor repertoires of B- and T-cells form the basis of the adaptive immune response. The repertoires should be sufficiently diverse to recognize all possible pathogens. However, careful selection is needed to prevent responses to self or harmless antigens. Limited antigen receptor repe...

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Detalles Bibliográficos
Autores principales: IJspeert, Hanna, Wentink, Marjolein, van Zessen, David, Driessen, Gertjan J., Dalm, Virgil A. S. H., van Hagen, Martin P., Pico-Knijnenburg, Ingrid, Simons, Erik J., van Dongen, Jacques J. M., Stubbs, Andrew P., van der Burg, Mirjam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389565/
https://www.ncbi.nlm.nih.gov/pubmed/25904919
http://dx.doi.org/10.3389/fimmu.2015.00157