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The tumour-promoting receptor tyrosine kinase, EphB4, regulates expression of Integrin-β8 in prostate cancer cells

BACKGROUND: The EphB4 receptor tyrosine kinase is overexpressed in many cancers including prostate cancer. The molecular mechanisms by which this ephrin receptor influences cancer progression are complex as there are tumor-promoting ligand-independent mechanisms in place as well as ligand-dependent...

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Detalles Bibliográficos
Autores principales: Mertens-Walker, Inga, Fernandini, Bruno C, Maharaj, Mohanan SN, Rockstroh, Anja, Nelson, Colleen C, Herington, Adrian C, Stephenson, Sally-Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389669/
https://www.ncbi.nlm.nih.gov/pubmed/25886373
http://dx.doi.org/10.1186/s12885-015-1164-6