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The tumour-promoting receptor tyrosine kinase, EphB4, regulates expression of Integrin-β8 in prostate cancer cells
BACKGROUND: The EphB4 receptor tyrosine kinase is overexpressed in many cancers including prostate cancer. The molecular mechanisms by which this ephrin receptor influences cancer progression are complex as there are tumor-promoting ligand-independent mechanisms in place as well as ligand-dependent...
Autores principales: | Mertens-Walker, Inga, Fernandini, Bruno C, Maharaj, Mohanan SN, Rockstroh, Anja, Nelson, Colleen C, Herington, Adrian C, Stephenson, Sally-Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389669/ https://www.ncbi.nlm.nih.gov/pubmed/25886373 http://dx.doi.org/10.1186/s12885-015-1164-6 |
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