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RNA-guided CRISPR-Cas technologies for genome-scale investigation of disease processes

From its discovery as an adaptive bacterial and archaea immune system, the clustered regularly interspaced short palindromic repeats (CRISPR)-Cas system has quickly been developed into a powerful and groundbreaking programmable nuclease technology for the global and precise editing of the genome in...

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Detalles Bibliográficos
Autores principales: Humphrey, Sean E, Kasinski, Andrea L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389696/
https://www.ncbi.nlm.nih.gov/pubmed/25888285
http://dx.doi.org/10.1186/s13045-015-0127-3