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RNA-guided CRISPR-Cas technologies for genome-scale investigation of disease processes
From its discovery as an adaptive bacterial and archaea immune system, the clustered regularly interspaced short palindromic repeats (CRISPR)-Cas system has quickly been developed into a powerful and groundbreaking programmable nuclease technology for the global and precise editing of the genome in...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389696/ https://www.ncbi.nlm.nih.gov/pubmed/25888285 http://dx.doi.org/10.1186/s13045-015-0127-3 |