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Dynamic analysis of platelet deposition to resolve platelet adhesion receptor activity in whole blood at arterial shear rate

Platelet activation is traditionally quantified using turbidimetric aggregometry, which reflects integrin α(IIb)β(3) activity, an important determinant of platelet function during pathophysiological thrombus formation. However, aggregometry does not recreate the shear conditions prevailing during th...

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Detalles Bibliográficos
Autores principales: Pugh, Nicholas, Bihan, Dominique, Perry, David J., Farndale, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389707/
https://www.ncbi.nlm.nih.gov/pubmed/24679363
http://dx.doi.org/10.3109/09537104.2014.893289