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Dynamic analysis of platelet deposition to resolve platelet adhesion receptor activity in whole blood at arterial shear rate
Platelet activation is traditionally quantified using turbidimetric aggregometry, which reflects integrin α(IIb)β(3) activity, an important determinant of platelet function during pathophysiological thrombus formation. However, aggregometry does not recreate the shear conditions prevailing during th...
Autores principales: | Pugh, Nicholas, Bihan, Dominique, Perry, David J., Farndale, Richard W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389707/ https://www.ncbi.nlm.nih.gov/pubmed/24679363 http://dx.doi.org/10.3109/09537104.2014.893289 |
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