Cargando…

The leukemia inhibitory factor (LIF) and p21 mediate the TGFβ tumor suppressive effects in human cutaneous melanoma

BACKGROUND: Cutaneous melanoma is the most lethal skin cancer and its incidence in developed countries has dramatically increased over the past decades. Localized tumors are easily treated by surgery, but advanced melanomas lack efficient treatment and are associated with very poor outcomes. Thus, u...

Descripción completa

Detalles Bibliográficos
Autores principales: Humbert, Laure, Ghozlan, Mostafa, Canaff, Lucie, Tian, Jun, Lebrun, Jean-Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389797/
https://www.ncbi.nlm.nih.gov/pubmed/25885043
http://dx.doi.org/10.1186/s12885-015-1177-1