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Predicting genome-wide DNA methylation using methylation marks, genomic position, and DNA regulatory elements
BACKGROUND: Recent assays for individual-specific genome-wide DNA methylation profiles have enabled epigenome-wide association studies to identify specific CpG sites associated with a phenotype. Computational prediction of CpG site-specific methylation levels is critical to enable genome-wide analys...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389802/ https://www.ncbi.nlm.nih.gov/pubmed/25616342 http://dx.doi.org/10.1186/s13059-015-0581-9 |