Predicting genome-wide DNA methylation using methylation marks, genomic position, and DNA regulatory elements

BACKGROUND: Recent assays for individual-specific genome-wide DNA methylation profiles have enabled epigenome-wide association studies to identify specific CpG sites associated with a phenotype. Computational prediction of CpG site-specific methylation levels is critical to enable genome-wide analys...

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Detalles Bibliográficos
Autores principales: Zhang, Weiwei, Spector, Tim D, Deloukas, Panos, Bell, Jordana T, Engelhardt, Barbara E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389802/
https://www.ncbi.nlm.nih.gov/pubmed/25616342
http://dx.doi.org/10.1186/s13059-015-0581-9

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