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Recovering Drug-Induced Apoptosis Subnetwork from Connectivity Map Data

The Connectivity Map (CMAP) project profiled human cancer cell lines exposed to a library of anticancer compounds with the goal of connecting cancer with underlying genes and potential treatments. Since the therapeutic goal of most anticancer drugs is to induce tumor-selective apoptosis, it is criti...

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Detalles Bibliográficos
Autores principales: Yu, Jiyang, Putcha, Preeti, Silva, Jose M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389823/
https://www.ncbi.nlm.nih.gov/pubmed/25883971
http://dx.doi.org/10.1155/2015/708563