AntiCD3Fv fused to human interleukin-3 deletion variant redirected T cells against human acute myeloid leukemic stem cells

BACKGROUND: Leukemic stem cells (LSCs) are frequently seen as a cause of treatment failure and relapse in patients with acute myeloid leukemia (AML). Thus, successful new therapeutic strategies for the treatment of AML should aim at eradicating LSCs. The identification of targets on the cell surface...

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Detalles Bibliográficos
Autores principales: Fan, Dongmei, Li, Zhenzhen, Zhang, Xiaolong, Yang, Yuqi, Yuan, Xiangfei, Zhang, Xiuli, Yang, Ming, Zhang, Yizhi, Xiong, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389834/
https://www.ncbi.nlm.nih.gov/pubmed/25879549
http://dx.doi.org/10.1186/s13045-015-0109-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389834/
https://www.ncbi.nlm.nih.gov/pubmed/25879549
http://dx.doi.org/10.1186/s13045-015-0109-5

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