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Sertoli cell-mediated differentiation of male germ cell-like cells from human umbilical cord Wharton’s jelly-derived mesenchymal stem cells in an in vitro co-culture system

BACKGROUND: Microenvironment signals play a critical role in directing the differentiation of stem cells. Sertoli cells (SCs) provide a unique microenvironment that is essential for germ cell differentiation. METHODS: Our previous study has demonstrated that human umbilical cord Wharton’s jelly-deri...

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Detalles Bibliográficos
Autores principales: Xie, Lichun, Lin, Limin, Tang, Qiuliu, Li, Weizhong, Huang, Tianhua, Huo, Xiao, Liu, Xiaoshan, Jiang, Jikai, He, Guyu, Ma, Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389972/
https://www.ncbi.nlm.nih.gov/pubmed/25644284
http://dx.doi.org/10.1186/s40001-014-0080-6