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Anxiolytic and antidepressant profile of the methanolic extract of Piper nigrum fruits in beta-amyloid (1–42) rat model of Alzheimer’s disease

BACKGROUND: Piper nigrum L. (Piperaceae) is employed in traditional medicine of many countries as analgesic, antiinflammatory, anticonvulsant, antioxidant, antidepressant and cognitive-enhancing agent. This study was undertaken in order to evaluate the possible anxiolytic, antidepressant and antioxi...

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Detalles Bibliográficos
Autores principales: Hritcu, Lucian, Noumedem, Jaurès A, Cioanca, Oana, Hancianu, Monica, Postu, Paula, Mihasan, Marius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389991/
https://www.ncbi.nlm.nih.gov/pubmed/25880991
http://dx.doi.org/10.1186/s12993-015-0059-7