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Single Administration of Ultra-Low-Dose Lipopolysaccharide in Rat Early Pregnancy Induces TLR4 Activation in the Placenta Contributing to Preeclampsia

Balanced immune responses are essential for the maintenance of successful pregnancy. Aberrant responses of immune system during pregnancy increase the risk of preeclampsia. Toll-like receptor 4 (TLR4) plays a crucial role in the activation of immune system at the maternal-fetal interface. This study...

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Detalles Bibliográficos
Autores principales: Xue, Pingping, Zheng, Mingming, Gong, Ping, Lin, Caimei, Zhou, Jianjun, Li, Yujing, Shen, Li, Diao, Zhenyu, Yan, Guijun, Sun, Haixiang, Hu, Yali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390151/
https://www.ncbi.nlm.nih.gov/pubmed/25853857
http://dx.doi.org/10.1371/journal.pone.0124001