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A DIseAse MOdule Detection (DIAMOnD) Algorithm Derived from a Systematic Analysis of Connectivity Patterns of Disease Proteins in the Human Interactome

The observation that disease associated proteins often interact with each other has fueled the development of network-based approaches to elucidate the molecular mechanisms of human disease. Such approaches build on the assumption that protein interaction networks can be viewed as maps in which dise...

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Detalles Bibliográficos
Autores principales: Ghiassian, Susan Dina, Menche, Jörg, Barabási, Albert-László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390154/
https://www.ncbi.nlm.nih.gov/pubmed/25853560
http://dx.doi.org/10.1371/journal.pcbi.1004120