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Dose-Dependent ATP Depletion and Cancer Cell Death following Calcium Electroporation, Relative Effect of Calcium Concentration and Electric Field Strength

BACKGROUND: Electroporation, a method for increasing the permeability of membranes to ions and small molecules, is used in the clinic with chemotherapeutic drugs for cancer treatment (electrochemotherapy). Electroporation with calcium causes ATP (adenosine triphosphate) depletion and cancer cell dea...

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Detalles Bibliográficos
Autores principales: Hansen, Emilie Louise, Sozer, Esin Bengisu, Romeo, Stefania, Frandsen, Stine Krog, Vernier, P. Thomas, Gehl, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390219/
https://www.ncbi.nlm.nih.gov/pubmed/25853661
http://dx.doi.org/10.1371/journal.pone.0122973