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Dose-Dependent ATP Depletion and Cancer Cell Death following Calcium Electroporation, Relative Effect of Calcium Concentration and Electric Field Strength
BACKGROUND: Electroporation, a method for increasing the permeability of membranes to ions and small molecules, is used in the clinic with chemotherapeutic drugs for cancer treatment (electrochemotherapy). Electroporation with calcium causes ATP (adenosine triphosphate) depletion and cancer cell dea...
Autores principales: | Hansen, Emilie Louise, Sozer, Esin Bengisu, Romeo, Stefania, Frandsen, Stine Krog, Vernier, P. Thomas, Gehl, Julie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390219/ https://www.ncbi.nlm.nih.gov/pubmed/25853661 http://dx.doi.org/10.1371/journal.pone.0122973 |
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