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Proteomic Analyses Uncover a New Function and Mode of Action for Mouse Homolog of Diaphanous 2 (mDia2)

mDia2 is an auto-inhibited Formin influencing actin dynamics upon conversion to the active conformation. mDia2 regulates actin-based protrusions and cell invasion, cell differentiation, vesicle trafficking, and cytokinesis. However, whether mDia2 has additional functions and how its action is functi...

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Detalles Bibliográficos
Autores principales: Isogai, Tadamoto, van der Kammen, Rob, Goerdayal, Soenita S., Heck, Albert J. R., Altelaar, A. F. Maarten, Innocenti, Metello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390252/
https://www.ncbi.nlm.nih.gov/pubmed/25682332
http://dx.doi.org/10.1074/mcp.M114.043885