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Deep Proteomics of Mouse Skeletal Muscle Enables Quantitation of Protein Isoforms, Metabolic Pathways, and Transcription Factors

Skeletal muscle constitutes 40% of individual body mass and plays vital roles in locomotion and whole-body metabolism. Proteomics of skeletal muscle is challenging because of highly abundant contractile proteins that interfere with detection of regulatory proteins. Using a state-of-the art MS workfl...

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Detalles Bibliográficos
Autores principales: Deshmukh, Atul S., Murgia, Marta, Nagaraj, Nagarjuna, Treebak, Jonas T., Cox, Jürgen, Mann, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390264/
https://www.ncbi.nlm.nih.gov/pubmed/25616865
http://dx.doi.org/10.1074/mcp.M114.044222