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Impact of the CFTR-Potentiator Ivacaftor on Airway Microbiota in Cystic Fibrosis Patients Carrying A G551D Mutation

BACKGROUND: Airway microbiota composition has been clearly correlated with many pulmonary diseases, and notably with cystic fibrosis (CF), an autosomal genetic disorder caused by mutation in the CF transmembrane conductance regulator (CFTR). Recently, a new molecule, ivacaftor, has been shown to re-...

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Detalles Bibliográficos
Autores principales: Bernarde, Cédric, Keravec, Marlène, Mounier, Jérôme, Gouriou, Stéphanie, Rault, Gilles, Férec, Claude, Barbier, Georges, Héry-Arnaud, Geneviève
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390299/
https://www.ncbi.nlm.nih.gov/pubmed/25853698
http://dx.doi.org/10.1371/journal.pone.0124124