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Calibration of the γ-H2AX DNA Double Strand Break Focus Assay for Internal Radiation Exposure of Blood Lymphocytes

DNA double strand break (DSB) formation induced by ionizing radiation exposure is indicated by the DSB biomarkers γ-H2AX and 53BP1. Knowledge about DSB foci formation in-vitro after internal irradiation of whole blood samples with radionuclides in solution will help us to gain detailed insights abou...

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Detalles Bibliográficos
Autores principales: Eberlein, Uta, Peper, Michel, Fernández, Maria, Lassmann, Michael, Scherthan, Harry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390303/
https://www.ncbi.nlm.nih.gov/pubmed/25853575
http://dx.doi.org/10.1371/journal.pone.0123174