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microRNA-155, Induced by Interleukin-1ß, Represses the Expression of Microphthalmia-Associated Transcription Factor (MITF-M) in Melanoma Cells

Loss of expression of surface antigens represents a significant problem for cancer immunotherapy. Microphthalmia-associated transcription factor (MITF-M) regulates melanocyte fate by driving expression of many differentiation genes, whose protein products can be recognized by cytolytic T lymphocytes...

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Detalles Bibliográficos
Autores principales: Arts, Nathalie, Cané, Stefania, Hennequart, Marc, Lamy, Juliette, Bommer, Guido, Van den Eynde, Benoît, De Plaen, Etienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390329/
https://www.ncbi.nlm.nih.gov/pubmed/25853464
http://dx.doi.org/10.1371/journal.pone.0122517